Strychnos nux-vomica L.
Traditional Knowledge
Useful plant parts :
Young shoot and leaf
Uses in traditional medicine :
- Young shoots with fresh leaves are ground into a paste and applied on wounds and ulcers
Scientific Research
Chemical constituents:
Indole alkaloids: strychnine, isostrychnine, protostrychnine, n-oxystrychnine, pseudostrychnine, brucine, brucine N-oxide, vomicine, strychnochrysine, strynuxlines A and B, hydroxycinnamic acid ester: chlorogenic acid, iridoid glucosides: loganic acid and its derivatives from seeds and roots
Bioactivity :
Alkaloids from seeds: anticancer; brucine and brucine-N-oxide: anti-inflammatory, antinociceptive; alcohol and aqueous extract of seeds: antihyperglycaemic
Clinical:
Note :
A poisonous plant in Sri Lanka
References : Biala, R. G. et al., (1998), Strychnochrysine, a New Bisindole Alkaloid from the Roots of Strychnos nux-vomica, Journal of Natural Products, 61(1), 139–141. Bhati, R. et al., (2012), Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity, J Ayurveda Integr Med, 3(2), 80-4. Deng, X. K. et al., (2006), The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism, Journal of Ethnopharmacology, 106(2), 179–186. Fu, Y. et al., (2012), Strynuxlines A and B, Alkaloids with an Unprec- edented Carbon Skeleton from Strychnos nux-vomica, J Nat Prod. Yin, W. et al., (2003), Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica, Journal of Ethnopharmacology, 88(2-3), 205-214. Zhang, X. et al., (2003), Iridoid glucosides from Strychnosnux-vomica: Reports on Structure Elucidation, Phytochemistry, 64(8), 1341–1344.
Copyrights Reserved By
Natures Beauty Creations
