Tabernaemontana divaricata (L.) R. Br. ex Roem. & Schult.
Traditional Knowledge
Useful plant parts :
Leaf, root and flower
Uses in traditional medicine :
- Ground fresh root is used as an anodyne
- Flower infusion is used for red eyes
- Latex is used to remove thorns from the skin
Scientific Research
Chemical constituents:
Triterpenes: cycloeucalenol and other cycloartane derivatives, indole alkaloids: 19, 20 dihydroervahanine, coronaridine, heyneanine, voacristine, voacamine, descarbomethoxyvoacamine, phenolic acids: vanillic, gentisic, syringic, 4-hydroxybenzoic and salicylic acids from stem
Bioactivity :
Methanol extract of leaves: antioxidative; hydroxyvocamine: acetylcholinesterase inhibitor; methanol extract of flower: antifertility activity
Clinical:
References : Chaiyana, W. et al., (2013), 3′-R/S-hydroxyvoacamine, a potent acetylcholinesterase inhibitor from Tabernaemontana divaricata, Phytomedicine. 20(6), 543-8. Gupta, M. et al., (2004), Antioxidant and Free Radical Scavenging Activities of Ervatamia coronaria Stapf. Leaves, Iranian Journal of Pharmaceutical Research, 3(2), 119-126. Henriques, A. T. et al., (1996), Ervatamia coronaria: chemical constitu- ents and some pharmacological activities, Journal of Ethnopharmacol- ogy, 50(1), 19-25. Mukhram, M. A. et al., (2012), Anti-fertility effect of flower extracts of Tabernaemontana divaricata in rats, Chin J Nat Med, 10(1), 58-62. Yang, Y. U. and Ji-Kai, L. I. U., (1999), The constituents of Ervatamia divaricata, ACTA Botanica Yunnanica, 2.
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