Tephrosia purpurea (L.) Pers.
Traditional Knowledge
Useful plant parts :
Whole plant, root and leaf
Uses in traditional medicine :
- Roots are used as a toothbrush for mouth sanitation
- Decoction of the whole plant is prescribed as a mouthwash
- Leaves are tonic to intestine (appetiser) and used in piles, syphilis and gonorrhoea
- Allays thirst, enriches blood, cures diarrhoea, bronchitis, asthma, inflammations, boils, pimples, tumours, ulcers, leprosy and to treat poisoning
- Acts as a digestive, anthelmintic, alexiteric, antipyretic and an alterative
- Used to treat diseases of the liver, spleen, heart and blood
Scientific Research
Chemical constituents:
Flavonoid glycosides: rutin, osyritin, retenoids: deguelin, elliptone, flavonoids: quercetin, lanceolatin A–C, tephrorins A and B, tephrosone, purpurin, purpurenone, purpuritenin and β-sitosterol from plant; prenylated flavonoids: tephropurpulin A and isoglabratephrin from aerial parts
Bioactivity :
Root extracts: cytoprotective, antiulcer; ethanol extract of aerial parts: hepatoprotective, wound healing; ethanol extract of roots: anticarcinogenic, antilipidperoxidative; methanol extract of whole plant: spasmolytic, bronchodilator, vasorelaxant; aqueous extract of leaves: antihyperglycaemic, antihyperlipidaemic
Clinical:
References : Chang, L. C. et al., (2000), Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea, Org Lett, 2(4), 515-8. Deshpande, S. S. et al., (2003), Antiulcer activity of Tephrosia purpurea in rats, Indian Journal of Pharmacology, 35, 168-172. Janbaz, K. H. et al., (2013), Spasmolytic, bronchodilator and vasorelax- ant activity of methanolic extract of Tephrosia purpurea, Acta Pol Pharm, 70(2), 261-9. Kavitha, K. and Manoharan, S., (2006), Anticarcinogenic and antilipid- peroxidative effects of Tephrosia purpurea (Linn.) Pers. in 7, 12-dimethylbenz (a) anthracene (DMBA) induced hamster buccal pouch carcinoma, Indian journal of pharmacology, 38(3), 185-189. Khatri, A. et al., (2009), Evaluation of hepatoprotective activity of aerial parts of Tephrosia purpurea L. and stem bark of Tecomella undulate, Journal of Ethnopharmacology, 122, 1–5. Lodhi, S. et al., (2006), Wound healing potential of Tephrosia purpurea (Linn.) Pers. in rats, Journal of Ethnopharmacology, 108, 204–210. Mohamed, E. F. H. et al., (2009), Rare prenylated flavonoids from Tephrosia purpurea, Phytochemistry, 70, 1474–1477. Pavana, P. et al., (2007), Antihyperglycemic and antihyperlipidemic effects of Tephrosia purpurea leaf extract in streptozotocin induced diabetic rats, J Environ Biol, 28(4), 833-7.
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