Alpinia calcarata (Haw.) Roscoe
Traditional Knowledge
Useful plant parts :
Rhizome
Uses in traditional medicine :
- Half a cup of powdered dried rhizome is taken morning and evening for rheumatic joint pains
- Used as a fomentation on rheumatic joints
- Steam of the fresh rhizome is inhaled to cure coughs and colds
Scientific Research
Chemical constituents:
Flavonoids: pinocembrin, pinobanksin, zerumin A, labdane type diterpenes: calcaratarins A−H, elemane type sesquiterpene: shyobunone from rhizomes
Bioactivity :
Pinocembrin: mitochondrial apoptosis in colon cancer cells; leaf extracts: antioxidative; essential oil and hydro alcohol extract of rhizomes: antifungal, antinociceptive, aphrodisiac, anti-inflammatory, anticancer
Clinical:
Rhizome is used as an ingredient of the polyherbal formulation “maharasnadi quatha” which is used for rheumatoid arthritis
References : Arambewela, L. S. R. et al., (2010), Antioxidant and antifungal activities of essential oil of Alpinia calcarata Roscoe, Journal of Ayurveda Integrative Medicine, 1(3), 199-202. Arambewela, L. S. et al., (2004), Antinociceptive activities of aqueous and ethanolic extracts of Alpinia calcarata rhizomes in rats, J Ethnophar- macol, 95(2-3), 311-6. Arawwawala, L. D. et al., (2012), Alpinia calcarata Roscoe: a potent antiinflammatory agent, J Ethnopharmacol, 139(3), 889-92. Hema, P. S. and Nair M.S. (2009), Flavonoids and other constituents from the rhizomes of Alpinia calcarata, Biochemical Systematics and Ecology, 37, 52–54. Kong, L.Y. et al., (2000), Diterpenoids from the rhizomes of Alpinia calcarata, J Nat Prod, 63(7), 939-42. Kong, L.Y. et al., (2002), New cytotoxic bis-labdanic diterpenoids from calcarata, Planta Med, 68(9), 813-7. Kumar, M. A. et al., (2007), Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells, Mol Carcinog, 46(3), 231-41. Narayanaswamy, N. and Balakrishnan, K. P., (2011), Evaluation of some Medicinal Plants for their Antioxidant Properties, International Journal of PharmTech Research, 3(1), 381-385. Paranagama. P. A. and Ekanayake, E. M. D. S., (2004), Repellant properties from essential oil of Alpinia calcarata Roscoe. against the American Cockroach, Periplanata americana, Journal of National Science Foundation Sri lanka, 32(1-2), 1-12. Perveen, R. et al., (2012), Preventive effect of ethanol extract of Alpinia calcarata Rosc on Ehrlich’s ascitic carcinoma cell induced malignant ascites in mice, Asian Pac J Trop Med, 5(2), 121-5. Ratnasooriya, W. D. and Jayakody, J. R., (2006), Effects of aqueous extract of Alpinia calcarata rhizomes on reproductive competence of male rats, Acta Biol Hung, 57(1), 23-35. Thabrew, M. I. et al., (2001), Antioxidant potential of two polyherbal preparations used in Ayurveda for the treatment of rheumatoid arthritis, Journal of Ethnopharmacology, 76, 285–291.
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