Biophytum reinwardtii (Zucc.) Klotzsch

Oxalidaceae

Synonym:

Biophytum sensitivum sensu Trimen

Common Names:
Gas-nidikumba (S)
Runakkali (T)
Jalapushpa, Panktipathra (Sa)

Traditional Knowledge

Useful plant parts :
Leaf

Uses in traditional medicine :

Thick decoction of the fresh leaves is taken as a remedy for cough
Crushed leaves are applied on cuts and wounds to stop bleeding and quick healing
Acts as a diuretic and an expectorant
Used to treat hypertension, asthma, phthisis, snake bite poisoning, gonorrhoea, stones in the bladder and to promote suppuration

Scientific Research

Chemical constituents:

Amentoflavone: 3′, 8’’-biapigenin from roots and stems; proanthocyanidins from roots and aerial parts; triterpene: lupeol and β-sitosterol and fatty acid: linoleic acid and palmitate from whole plant

Bioactivity :

Methanol, acetone and chloroform extracts of leaves: hypoglycaemic, antibacterial; aqueous extracts of roots and aerial parts: anti-inflammatory; amentoflavone: induce apoptosis; alcoholic extract of plant: immunomodulator and antitumour

Clinical:

References :

Bharati, A. C. and Sahu, A. N., (2012), Ethnobotany, phytochemistry and pharmacology of Biophytum sensitivum DC., Pharmacogn Rev, 6(11), 68-73.

Buca, F. et al., (1998), Amentoflavone from Biophytum sensitivum and its Effect on COX-1/COX-2 Catalysed Prostaglandin Biosynthesis, Planta Med, 64(4), 373-374.

Guruvayoorappan, C. and Kuttan, G., (2007), Immunomodulatory and Antitumor Activity of Biophytum sensitivum Extract, Asian Pacific Journal of Cancer Prevention, 8, 27-32.

Jachak, S. M. et al., (1999), Antiinflammatory Activity of Extracts of Biophytum sensitivum in Carrageenin-induced rat paw oedema, Phytotherapy Research, 13, 73-74.

Natarajan, D. et al., (2010), Antibacterial activity of leaf extracts of Biophytum sensitivum (L.) DC., Journal of Agricultural and Food Chemistry, 2(11), 717-720.

Puri, D., (2001), The insulinotropic activity of a Nepalese medicinal plant Biophytum sensitivum: preliminary experimental study, Journal of Ethnopharmacology, 78, 89-93.

Sakthivel, K. M. and Guruvayoorappan, C., (2012), Biophytum sensiti- vum: Ancient medicine, modern targets, J Adv Pharm Technol Res, 3(2), 83-91.

Siveen, K. S. and Kuttan, G., (2011), Effect of amentoflavone, a phenolic component from Biophytum sensitivum, on cell cycling and apoptosis of B16F-10 melanoma cells, J Environ Pathol Toxicol Oncol, 30(4), 301-9.

Srinivasan, G. V. et al., (2008), Chemical compounds in Biophytum reinwardtii and their antioxidant potential, Journal of Tropical Medicinal Plants, 9(2), 338-342.

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