Evolvulus alsinoides (L.) L.
Traditional Knowledge
Useful plant parts :
Whole plant
Uses in traditional medicine :
- Half a tea spoon of powder made of washed mature plant, dried under shade is mixed with ghee and taken orally for memory loss
Scientific Research
Chemical constituents:
Flavonoid glycosides: evolvulus C–E, chlorogenic acid: caffeoylquinic acid derivatives and caffeic acid, coumarins and coumarin glycosides: scopoletin, umbelliferone, scopolin and polyhydroxy alcohol: butanetetrol derivative from plant
Bioactivity :
Crude ethanol extract of whole plant: adaptogenic, antiamnesic; caffeoylquinic acid derivatives and caffeic acid: antistress, normalize hyperglycaemia, plasma corticosterone levels and adrenal hypertrophy; alcohol extract of plant: antiulcer, anticatatonic, memory enhancing effects, anxiolytic, antioxidative, reduce pancreatic oxidative stress and increase insulin levels in diabetes
Clinical:
Ingredient of the tablet ‘Mentat’ which serves as an adjuvant to antiepileptic drugs
References : Cervenka, F. et al., (2008), Evaluation of natural substances from Evolvulus alsinoides L. with the purpose of determining their antioxidant potency, Journal of Enzyme Inhibition and Medicinal Chemistry, 23(4), 574-578. Gomathi, D. et al., (2013), Efficacy of Evolvulus alsinoides (L.) L. on insulin and antioxidants activity in pancreas of streptozotocin induced diabetic rats, J Diabetes Metab Disord, 12(1), 39. Gupta, P. et al., (2013), Evolvosides C–E, flavonol-4′-O-triglycosides from Evolvulus alsinoides and their anti-stress activity, Bioorg Med Chem, 21(5), 1116-22. Kumar, M. et al., (2010), Antioxidant flavonoid glycosides from Evolvulus alsinoides, Fitoterapia, 81(4), 234-242. Moharana, D. and Moharana, S., (1994), A Clinical Trial of Mentat in Patients with Various Types of Epilepsy, Probe, 2, 160-162. Nahata, A. et al., (2009), Anxiolytic activity of Evolvulus alsinoides and Convulvulus pluricaulis in rodents, Pharmaceutical Biology, 47(5), 444-451. Nahata, A. et al., (2010), Effect of Evolvulus alsinoides Linn. on learning behavior and memory enhancement activity in rodents, Phytotherapy Research, 24(4), 486-493. Purohit, M. G., (1996), Antiulcer And Anticatatonic Activity Of Alcoholic Extract Of Evolvulus alsinoides (Convolvulaceae), Indian Journal of Pharmaceutical Science, 58(3), 110-112. Siripurapu, K. B. et al., (2005), Adaptogenic and anti-amnesic properties of Evolvulus alsinoidesin rodents, Pharmacology Biochemistry and Behavior, 81(3), 424-432.
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